4275-4280
Antimalarial, Antiproliferative, and Antitumor Activities of Artemisinin-Derived, Chemically Robust, Trioxane Dimers
ARTICLES
4281-4291
Synthesis of Novel GABA Uptake Inhibitors. 4. Bioisosteric Transformation and Successive Optimization of Known GABA Uptake Inhibitors Leading to a Series of Potent Anticonvulsant Drug Candidates
rensen,
4292-4299
Novel Series of Non-Glycerol-Based Cationic Transfection Lipids for Use in Liposomal Gene Delivery
4300-4312
Design, Synthesis, and Evaluation of Inhibitors of Trypanosomal and Leishmanial Dihydrofolate Reductase
4313-4324
Free Energy Grids: A Practical Qualitative Application of Free Energy Perturbation to Ligand Design Using the OWFEG Method
4325-4330
Crystal Structure of Human DT-diaphorase: A Model for Interaction with the Cytotoxic Prodrug 5-(Aziridin-1-yl)-2,4-dinitrobenzamide (CB1954)
4331-4342
Design, Synthesis, and Evaluation of Phe-Gly Mimetics: Heterocyclic Building Blocks for Pseudopeptides
4343-4350
Structure-Activity Relationships and Molecular Modeling Analysis of Flavonoids Binding to the Benzodiazepine Site of the Rat Brain GABAA Receptor Complex
4351-4361
Enantiospecific Synthesis of 3-Fluoromethyl-, 3-Hydroxymethyl-, and 3-Chloromethyl-1,2,3,4-tetrahydroisoquinolines as Selective Inhibitors of Phenylethanolamine N-Methyltransferase versus the 
2-Adrenoceptor
4362-4379
Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure-Activity Relationships, and Biological Studies
4380-4387
Compounds That Activate the Mouse Melanocortin-1 Receptor Identified by Screening a Small Molecule Library Based upon the 
-Turn
4388-4393
New Natural Sesquiterpenes as Modulators of Daunomycin Resistance in a Multidrug-Resistant Leishmania tropica Line
4394-4404
Evaluation and Biological Properties of Reactive Ligands for the Mapping of the Glycine Site on the N-Methyl-D-aspartate (NMDA) Receptor
4405-4413
New Tetracyclic Analogues of Photochemotherapeutic Drugs 5-MOP and 8-MOP: Synthesis, DNA Interaction, and Antiproliferative Activity
4414-4421
Synthesis and Anticonvulsant Activity of Novel and Potent 2,3-Benzodiazepine AMPA/Kainate Receptor Antagonists
4422-4433
Two-Stage Method for Protein-Ligand Docking
4434-4445
Heteroarotinoids Inhibit Head and Neck Cancer Cell Lines in Vitro and in Vivo Through Both RAR and RXR Retinoic Acid Receptors
4446-4455
Structure-Activity Relationships at the Monoamine Transporters and 
Receptors for a Novel Series of 9-[3-(cis-3,5-Dimethyl-1-piperazinyl)-propyl]carbazole (Rimcazole) Analogues
BRIEF ARTICLES
4456-4461
Retention of Immunosuppressant Activity in an Ascomycin Analogue Lacking a Hydrogen-Bonding Interaction with FKBP12
4462-4470
Pyrrolobenzoxazepinone Derivatives as Non-Nucleoside HIV-1 RT Inhibitors: Further Structure-Activity Relationship Studies and Identification of More Potent Broad-Spectrum HIV-1 RT Inhibitors with Antiviral Activity
BOOK REVIEWS
4471-4471
Handbook of Drug Metabolism Edited by Thomas F. Woolf. Marcel Dekker, New York. 1999. xi + 596 pp. 18 × 26 cm. ISBN 0-8247-0229-8. $225.00.
4472-4472
Protein Purification. Principles, High-Resolution Methods, and Applications. 2nd Edition Edited by Jan-Christer Janson and Lars Ryden. Wiley-Liss, John Wiley & Sons, Inc., New York. 1998. x + 695 pp. 16 x 24 cm. ISBN 0-471-18626-0. $74.95.